Neeraj Wadhwa,¹ Pranav More,¹ Seema Sen,² Pradeep Venkatesh,¹ Sat Pal Garg^1
1Dr Rajendra Prasad Centre for Ophthalmic Sciences, and ²Department of Ocular Pathology, All India Institute of Medical Sciences, New Delhi, India

Histiocytic disorders are rare and often unsuspected. There is biological and histopathological overlap that is often confounding. The presentations and natural history are often varied and ill defined. Periorbital xanthogranuloma in adults is rare and may be part of systemic involvement that might include para-proteinaemias, leukaemias, and Erdheim-Chester disease. Diagnosis is usually confirmed by histopathology. Intraocular involvement is rare. This report is of a patient whose clinical presentation included atypical periorbital and intraorbital lesions with presumed retinal infiltration.

Key words: Histiocytic disorders, malignant, Orbit, Retina

Asian J Ophthalmol. 2007;9:134-137.