Priyanka Sharma, VP Gupta, Rohit Sharma
Department of Ophthalmology, University College of Medical Sciences, Delhi, India

Aim: To report the results of non-penetrating deep sclerectomy with deroofing of Schlemm's
canal with intraoperative mitomycin C in eyes with primary open angle glaucoma.
Methods: This prospective study included 33 eyes of 33 patients with newly diagnosed primary open angle glaucoma. Non-penetrating deep sclerectomy with deroofing of Schlemm's canal with intraoperative mitomycin C was performed for all patients. Visual acuity, intraocular pressure, anterior chamber depth measurement, and slit-lamp examination were performed preoperatively and postoperatively at 1 and 5 days and 1, 3, 6, 9, 12, 15, 18, and 21 months.
Results: The complete success rate, defined as an intraocular pressure ≤21 mmHg and ≥30% intraocular pressure reduction without medication, was 96.9% at 15 months. Visual acuity remained stable. No significant change in anterior chamber depth occurred. Complications included microperforations (9%), shallow dissection (3%), haemorrhage in the bleb region (9%), and conjunctival wound gape without leak (6%).
Conclusion: Non-penetrating deep sclerectomy with deroofing of Schlemm's canal with mitomycin C appears to be a safe and highly effective technique for primary open angle glaucoma, without serious complications.

Key words: Glaucoma, open angle, Surgery

Asian J Ophthalmol. 2007;9:111-116.