| Past Issue | Volume 9 Number 2 April 2007 | | Blepharophimosis Syndrome and its Association with Amblyopia and Refractive Errors in a South Indian Population |
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Jitendra Jethani,1 Usha Kim,2 Hadi Kharzei,2 Perumalsamy Vijayalakshmi3
1Paediatric Ophthalmology and Strabismus Clinic, M&J Western Regional Institute of Ophthalmology, Civil Hospital, Ahmedabad, 2Orbit and Oculoplasty Clinic, and 3Paediatric Ophthalmology and Strabismus Clinic, Aravind Eye Hospitals, Madurai, India
Aim: To study refractive errors, strabismus, and amblyopia, in patients presenting with blepharophimosis ptosis epicanthus inversus syndrome.
Methods: Seventy three patients with blepharophimosis syndrome attending a tertiary eye care centre in Madurai, India, from January 1997 to January 2003 were enrolled in this retrospective interventional case series. All patients underwent complete ocular examination, which included measurement of the horizontal and vertical palpebral aperture with a ruler and measurement of levator function by Berke’s method. Cycloplegic refraction and orthoptic examination were performed by a trained orthoptist.
Results: Amblyopia was present in 23 patients (31.5%) and 62 eyes (42.5%) had some form of refractive error. The latter included 30 eyes (20.5%) with high myopia. Surgical correction (frontalis sling) was performed in 63 patients (86.3%). Nine patients (12.3%) had strabismus, all of whom were children; 5 had esotropia, 2 had exotropia, and 2 had vertical deviation. All 9 patients had amblyopia.
Conclusions: Refractive errors, amblyopia, and strabismus were commonly associated with blepharophimosis syndrome. However, amblyopia was present less frequently than reported previously. A high proportion of patients were found to have high myopia.
Key words: Amblyopia, Blepharophimosis, Myopia, Refractive errors
Asian J Ophthalmol. 2007;9:68-71.
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