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Past IssueVolume 8, Number 1, 2006
Evaluation of Outcome of Amniotic Membrane Transplantation with Conjunctival Limbal Autograft for Pterygium

Virender S Sangwan, Balasubramanya Ramamurthy, Sameer G Datar

Cornea and Anterior Segment Services, LV Prasad Eye Institute, Hyderabad, India

Aim: To determine the outcome of amniotic membrane transplant with conjunctival limbal autografts for primary and recurrent pterygium.
Patients and Methods: Ninety one eyes of 86 patients were reviewed in this retrospective non-comparative interventional case series. Fifty four eyes (59.3%) had primary pterygium and 37 eyes (40.7%) had recurrent pterygium. Of these, 11 eyes (12.1%) had symblepharon and 8 eyes (8.8%) had ocular motility restriction. There was a male preponderance with 74.4% men and 25.6% women The majority of patients (76.7%) worked indoors. All eyes were treated with amniotic membrane transplant along with conjunctival limbal autografts, and intraoperative mitomycin C was added for 7 eyes (7.7%) with recurrent pterygium. All surgeries were done by the same surgeon. The main outcome measures were recurrence of pterygium, improvement in ocular movement, and symblepharon formation.
Results: No recurrence was seen in 74 eyes (81.3%), 17 eyes (18.7%) had developed recurrence at the last follow up. None of the 7 patients with recurrent pterygium treated with adjunctive mitomycin C showed recurrence after the procedure. Recurrence of pterygium was seen in 9 eyes (16.6%) with primary pterygium and 8 eyes (21.6%) eyes with recurrent pterygium. All 8 eyes with restricted ocular motility showed improvement. There was no recurrence of symblepharon after surgery.
Conclusion: Amniotic membrane transplantation along with conjunctival limbal autograft is a safe procedure for ocular surface reconstruction after pterygium excision in patients with restricted ocular motility and symblepharon formation.

Key Words: Amnion, Conjunctiva, Pterygium, Reconstructive surgical procedures, Transplantation, autologous, Transplants
Asian J Ophthalmol 2006;8(1):20-23.
 
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