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 Volume 10 Number 4 August 2008
Successful Treatment of Aspergillus flavus Sclerokeratitis 8 Years after Pterygium Excision


Mahiran Che Daud,1 Mohtar Ibrahim,1 Shamala Retnasabapathy2
1Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, and 2Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia

This report is of a patient with Aspergillus flavus sclerokeratitis noted 8 years after pterygium excision. A 61 year-old man with diabetes mellitus was referred to the Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia, with right eye pain and redness for the previous 2 weeks. He had no history of trauma, but had had pterygium excision and cataract surgery performed 8 years previously. Examination of the right eye revealed right nasal scleral necrosis with calcification and a stromal abscess suggestive of fungal keratitis adjacent to the lesion. Corneal scraping revealed Aspergillus flavus. The patient responded well to treatment with topical and oral fluconazole and topical amphotericin B 0.15% and, after 5 weeks, the scleral necrosis had become epithelised, and the stromal abscess and plaque regressed. Early diagnosis is important, and aggressive medical treatment will improve the outcome.

Key words: Aspergillus flavus, Cornea, Eye infections, fungal, Pterygium, Sclera

Asian J Ophthalmol. 2008;10:233-235.

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